Article
slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains.
Genes & development - 1 Dec 1990
Rothberg J M, Jacobs J R, Goodman C S, Artavanis-Tsakonas S
Abstract excerpt
The Drosophila slit locus encodes a protein with four regions containing tandem arrays of a 24-amino-acid leucine-rich repeat (LRR) with conserved flanking sequences (flank-LRR-flank surrounding these arrays), followed by two regions with epidermal growth factor (EGF)-like repeats. Each of these...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Axons
- Base Sequence
- DNA Transposable Elements
- Drosophila
- Drosophila Proteins
- Epidermal Growth Factor
- Immunohistochemistry
- Leucine
- Molecular Sequence Data
- Nerve Tissue Proteins
- Neural Pathways
- Neuroglia
- Proteins
- Repetitive Sequences, Nucleic Acid
- Restriction Mapping