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Article

Expression of GFRalpha1 receptor splicing variants with different biochemical properties is modulated during kidney development.

Cellular signalling - 1 Dec 2004

Charlet-Berguerand Nicolas, Le Hir Hervé, Incoronato Mariarosaria, di Porzio Umberto, Yu Yanbin, Jing Shuqian, de Franciscis Vittorio, Thermes Claude

Abstract excerpt

The glial cell line-derived neurotrophic factor (GDNF) family coreceptor alpha1 (GFRalpha1) is a critical component of the RET receptor kinase signal-transducing complex. The activity of this multicomponent receptor is stimulated by the glial cell line-derived neurotrophic factor (GDNF) and is involved in neuronal cells survival and kidney development. GFRalpha1 pre-mRNA is alternatively spliced and produces two...

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Identifiers

PMID: 15381258
DOI: 10.1016/j.cellsig.2004.05.006

Genes

GDNF
RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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