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Article

Elastin-derived peptides enhance angiogenesis by promoting endothelial cell migration and tubulogenesis through upregulation of MT1-MMP.

Journal of cell science - 15 Jan 2005

Robinet Arnaud, Fahem Abdel, Cauchard Jean-Hubert, Huet Eric, Vincent Loïc, Lorimier Sandrine, Antonicelli Franck, Soria Claudine, Crepin Michel, Hornebeck William, Bellon Georges

Abstract excerpt

Elastin-derived peptides display a wide range of biological activities in a number of normal and transformed cells but their involvement in angiogenesis has not been reported. In the present study, we show that kappa-elastin and VGVAPG hexapeptide elastin motif accelerated angiogenesis in the chick chorio-allantoic membrane in an in vivo model. They also stimulated pseudotube formation from human vascular and...

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Identifiers

PMID: 15632106
DOI: 10.1242/jcs.01613

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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