Article
Elastin induces myofibrillogenesis via a specific domain, VGVAPG.
Matrix biology : journal of the International Society for Matrix Biology - 1 Sept 2003
Karnik Satyajit K, Wythe Joshua D, Sorensen Lise, Brooke Benjamin S, Urness Lisa D, Li Dean Y
Abstract excerpt
A hallmark of vascular smooth muscle cells (VSMCs) is their dynamic ability to assemble and disassemble contractile proteins into sarcomeric units depending upon their phenotypic state. This phenotypic plasticity plays an important role during vascular development and in obstructive vascular disease. Previously, we showed that the Elastin gene product, tropoelastin, activates myofibrillar organization of VSMCs....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
