Article
Electrospun elastin-like polypeptide enriched polyurethanes and their interactions with vascular smooth muscle cells.
Acta biomaterialia - 1 Jul 2012
Blit Patrick H, Battiston Kyle G, Yang Meilin, Paul Santerre J, Woodhouse Kimberly A
Abstract excerpt
In vascular tissue, elastin is an essential extracellular matrix protein that plays an important biomechanical and biological signalling role. Native elastin is insoluble and is difficult to extract from tissues, which results in its relatively rare use for the fabrication of vascular tissue engineering scaffolds. Recombinant elastin-like polypeptide-4 (ELP4), which mimics the structure and function of native...
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