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Article

Molecular responses of choroidal endothelial cells to elastin derived peptides through the elastin-binding protein (GLB1).

Matrix biology : journal of the International Society for Matrix Biology - 1 Mar 2012

Skeie Jessica M, Hernandez Jasmine, Hinek Aleksander, Mullins Robert F

Abstract excerpt

PURPOSE: Neovascular AMD involves the activation of choroidal endothelial cells to increase their inflammatory and angiogenic behaviors. Elastin derived peptides (EDPs) can elicit some of these phenotypic changes in endothelial cells. This investigation was performed to follow up on those findings by determining a receptor for these peptides in the human eye as well as evaluating the effects of elevated EDPs on...

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Share to Cathepsin A
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neovascularization, Pathologic

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Source

Open in PubMed Open full text

Identifiers

PMID: 22178079
DOI: 10.1016/j.matbio.2011.11.003
PMCID: PMC3288713

Genes

GLB1
RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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