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Article

Design and synthesis of elastin-like polypeptides for an ideal nerve conduit in peripheral nerve regeneration.

Materials science & engineering. C, Materials for biological applications - 1 May 2014

Hsueh Yu-Sheng, Savitha S, Sadhasivam S, Lin Feng-Huei, Shieh Ming-Jium

Abstract excerpt

The study involves design and synthesis of three different elastin like polypeptide (ELP) gene monomers namely ELP1, ELP2 and ELP3 that encode for ELP proteins. The formed ELPs were assessed as an ideal nerve conduit for peripheral nerve regeneration. ELP1 was constructed with a small elongated pentapeptide carrying VPGVG sequence to mimic the natural polypeptide ELP. The ELP2 was designed by the incorporation of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24656360
DOI: 10.1016/j.msec.2014.01.058

Genes

ELP1
ELP2
ELP3
SDS

Provenance

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