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Article

Cost-effective genotyping of human MBL2 gene mutations using multiplex PCR.

Journal of immunological methods - 1 Dec 2004

Skalníková Helena, Freiberger Tomás, Chumchalová Jitka, Grombiríková Hana, Sedivá Anna

Abstract excerpt

Mannose-binding lectin (MBL) deficiency is associated with increased susceptibility to various infections and autoimmune disorders. It is caused by certain polymorphisms in the MBL2 gene promoter and mutations in the coding region of the gene. In this report, we present a novel, rapid, efficient and cost-effective method of two multiplex polymerase chain reactions (PCRs) for the assessment of three structural...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15627619
DOI: 10.1016/j.jim.2004.10.007

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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