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Article

Rapid genotyping of MBL2 gene mutations using real-time PCR with fluorescent hybridisation probes.

Journal of immunological methods - 1 Jul 2003

Steffensen R, Hoffmann K, Varming K

Abstract excerpt

In this study, we describe a real-time polymerase chain reaction (PCR) for genotyping all known polymorphisms of the human mannose-binding lectin 2 (MBL2) gene. These comprised two variations in the 5' regulatory region at positions -550 (H/L) and -221 (X/Y), one in the 5' untranslated sequence at position +4 (P/Q) and three structural mutations within exon 1 at codons 52, 54, and 57, also known as the D, B and C...

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Share to DNA Mutational Analysis
Share to DNA Primers
Share to In Situ Hybridization, Fluorescence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mannose-Binding Lectin

Share to Nucleic Acid Amplification Techniques

Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 12957407
DOI: 10.1016/s0022-1759(03)00190-x

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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