Article
MBL2 single nucleotide polymorphism diversity among four ethnic groups as revealed by a bead-based liquid array profiling.
Human immunology - 1 Dec 2008
Ivanova Milena, Ruiqing Ju, Matsushita Masaki, Ogawa Takahiro, Kawai Shintaro, Ochiai Naoya, Shivarov Velizar, Maruya Etsuko, Saji Hiroh
Abstract excerpt
In the present work we established a rapid, cost-effective and high-throughput method for genotyping using a multiplexed microsphere-based suspension array platform - Luminex xMAP which enabled us to analyze 3 SNPs in the MBL2 gene promoter and 5' UTR, and 3 coding SNPs exon 1 haplotypes, associated with different levels of MBL2 expression. Using this system MBL2 diversity in four different ethnic groups, namely,...
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