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Article

Structure and regulation of Kit protein-tyrosine kinase--the stem cell factor receptor.

Biochemical and biophysical research communications - 23 Dec 2005

Roskoski Robert

Abstract excerpt

Signaling by stem cell factor and Kit, its receptor, play important roles in gametogenesis, hematopoiesis, mast cell development and function, and melanogenesis. Moreover, human and mouse embryonic stem cells express Kit transcripts. Stem cell factor exists as both a soluble and a membrane-bound glycoprotein while Kit is a glycoprotein receptor protein-tyrosine kinase. The complete absence of stem cell factor or...

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Identifiers

PMID: 16226710
DOI: 10.1016/j.bbrc.2005.09.150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structure and regulation of Kit protein-tyrosine kinase--the stem cell factor receptor.PMID 16226710Read ↗

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