Article
Spindle assembly checkpoint genes reveal distinct as well as overlapping expression that implicates MDF-2/Mad2 in postembryonic seam cell proliferation in Caenorhabditis elegans.
BMC cell biology - 21 Sept 2010
Tarailo-Graovac Maja, Wang Jun, Chu Jeffrey S C, Tu Domena, Baillie David L, Chen Nansheng
Abstract excerpt
BACKGROUND: The spindle assembly checkpoint (SAC) delays anaphase onset by inhibiting the activity of the anaphase promoting complex/cyclosome (APC/C) until all of the kinetochores have properly attached to the spindle. The importance of SAC genes for genome stability is well established; however, the roles these genes play, during postembryonic development of a multicellular organism, remain largely unexplored....
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