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Article

Solvent Exposure, Genetic Susceptibility, and Risk of Bladder Cancer.

Cancer prevention research (Philadelphia, Pa.) - 1 May 2025

Tadesse Deborah A, Rothman Nathaniel, Xie Shuai, Hurwitz Lauren M, Friesen Melissa C, Baris Dalsu, Schwenn Molly, Johnson Alison, Karagas Margaret R, Silverman Debra T, Koutros Stella

Abstract excerpt

The New England Bladder Cancer Study has recently reported an increased bladder cancer risk with occupational exposure to mononuclear aromatic organic solvents, including exposure to benzene, toluene, and xylene and their combination BTX. However, the mechanisms by which BTX influence bladder cancer are unclear. In this study, we evaluated the interaction between BTX and genetic markers in known bladder cancer...

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Source

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Identifiers

PMID: 39995157
DOI: 10.1158/1940-6207.CAPR-24-0434
PMCID: PMC12045719

Genes

FGFR3
GSTT1

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