Article
Polyamines modulate carcinogen-induced mutagenesis in vivo.
Environmental and molecular mutagenesis - 1 Jan 2005
Wallon U Margaretha, O'Brien Thomas G
Abstract excerpt
Elevated polyamine levels as a consequence of targeted overexpression of ornithine decarboxylase (ODC) to murine skin enhance susceptibility to tumorigenesis in this tissue. A possible mechanism for the enhanced susceptibility phenotype is an increased sensitivity of tissues with elevated polyami...
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