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Article

Genetic aberrations in soft tissue leiomyosarcoma.

Cancer letters - 8 Mar 2009

Yang Jilong, Du Xiaoling, Chen Kexin, Ylipää Antti, Lazar Alexander J F, Trent Jonathan, Lev Dina, Pollock Raphael, Hao Xishan, Hunt Kelly, Zhang Wei

Abstract excerpt

Leiomyosarcoma is a malignant mesenchymal tumor composed of cells showing smooth muscle differentiation. This tumor usually occurs in middle-aged or older adults, and forms a significant percentage of retroperitoneal, vascular, extremity, and uterine sarcomas. Leiomyosarcomas are most often associated with complex karyotypes with numerous chromosomal gains and losses. Some of these cytogenetic and molecular...

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Identifiers

PMID: 18649996
DOI: 10.1016/j.canlet.2008.06.013
PMCID: PMC2674272

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