Virus-specific T cells in the central nervous system following infection with an avirulent neurotropic mouse hepatitis virus.

Article

Virus-specific T cells in the central nervous system following infection with an avirulent neurotropic mouse hepatitis virus.

Regional immunology - 1 Jan 2000

Williamson J S

Abstract excerpt

Intracerebral infection of mice with the neurotropic JHM strain of mouse hepatitis virus usually results in a fatal encephalomyelitis. However, infection with the neutralization resistant mutant, 2.2/7.2-V-2, results in inflammatory cell infiltration of the central nervous system with no apparent...

Topics

Animals
Antigens, Viral
Central Nervous System
Cytokines
Encephalomyelitis
Genetic Variation
Hepatitis, Viral, Animal
Lymphocyte Activation
Mice
Mice, Inbred C57BL
Murine hepatitis virus
Phenotype
T-Lymphocytes
Virulence

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