Unique sequence and lesional tropism of a new variant of neuropathogenic friend murine leukemia virus.

doi:10.1006/viro.1997.8619

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Article

Unique sequence and lesional tropism of a new variant of neuropathogenic friend murine leukemia virus.

Virology - 7 Jul 1997

Takase-Yoden S, Watanabe R

Abstract excerpt

FrC6 murine leukemia virus (MuLV) is a replication-competent, neuropathogenic variant derived from Friend MuLV (F-MuLV) complex. The A8 virus (a molecular clone of the FrC6 virus) induced marked spongiform degeneration in the brain similar to the FrC6 virus, but only mild lesions were found in th...

Topics

3T3 Cells
Animals
Base Sequence
Brain Diseases
Cell Line
Central Nervous System
Chromosome Mapping
Cloning, Molecular
DNA, Viral
Friend murine leukemia virus
Genes, env
Genetic Variation
Mice
Molecular Sequence Data
Nerve Degeneration
Neuroglia
Rats
Rats, Inbred F344

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