Article
Ultrastructural demonstration of mercury granules in the placenta of metallothionein-null pregnant mice after exposure to mercury vapor.
Toxicologic pathology - 1 Jan 2000
Shimada Akinori, Yamamoto Emi, Morita Takehito, Yoshida Minoru, Suzuki Junko S, Satoh Masahiko, Tohyama Chiharu
Abstract excerpt
The placenta plays an important role in the regulation of maternal to fetal transfer of toxic substances, including nonessential metals. Metallothioneins (MTs), which are known to have protective effects against heavy metal toxicity, exist in the placenta, but the exact localization of placental MTs (both MT-I and MT-III) and their physiological role in the placenta exposed to mercury are unclear. The present...
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