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Article

Metallothionein-I- and -II-deficient mice display increased susceptibility to cadmium-induced fetal growth restriction.

American journal of physiology. Endocrinology and metabolism - 15 Sept 2013

Selvaratnam Johanna, Guan Haiyan, Koropatnick James, Yang Kaiping

Abstract excerpt

Maternal cadmium exposure induces fetal growth restriction (FGR), but the underlying mechanisms remain largely unknown. The placenta is the main organ known to protect the fetus from environmental toxins such as cadmium. In this study, we examine the role of the two key placental factors in cadmium-induced FGR. The first is placental enzyme 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2), which is known to...

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Source

Identifiers

PMID: 23880315
DOI: 10.1152/ajpendo.00157.2013

Genes

FGR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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