An isoform of eIF4E is a component of germ granules and is required for spermatogenesis inC. elegans

Abstract excerpt

Control of gene expression at the translational level is crucial for many developmental processes. The mRNA cap-binding protein, eIF4E, is a key player in regulation of translation initiation; appropriate levels of eIF4E are essential for normal cell-cycle regulation and tissue differentiation. The observation that eIF4E levels are elevated during gametogenesis in several organisms suggests that eIF4E might have...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to CRISPR and Genetic Engineering
• Share to Genetics, Aging, and Longevity in Model Organisms
• Share to Reproductive Biology and Fertility