Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Balance of MafB and PU.1 specifies alternative macrophage or dendritic cell fate.

Blood - 1 Apr 2005

Bakri Youssef, Sarrazin Sandrine, Mayer Ulrich P, Tillmanns Silke, Nerlov Claus, Boned Annie, Sieweke Michael H

Abstract excerpt

Macrophages and myeloid dendritic cells (DCs) represent alternative differentiation options of bone marrow progenitors and blood monocytes. This choice profoundly influences the immune response under normal and pathological conditions, but the underlying transcriptional events remain unresolved. Here, we show that experimental activation of the transcription factors PU.1 and MafB in transformed chicken myeloid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chick Embryo
Share to Dendritic Cells
Share to Down-Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HL-60 Cells

Share to MafB Transcription Factor

Share to Monocytes

Share to Oncogene Proteins

Share to Transformation, Genetic

Source

Identifiers

PMID: 15598817
DOI: 10.1182/blood-2004-04-1448

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Balance of MafB and PU.1 specifies alternative macrophage or dendritic cell fate.PMID 15598817Read ↗

MafB is an inducer of monocytic differentiation.Semantic proximity Read ↗

PU.1, a shared transcriptional regulator of lymphoid and myeloid cell fates.Semantic proximity Read ↗

PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors.Semantic proximity Read ↗

Zbtb14 regulates monocyte and macrophage development through inhibiting <i>pu.1</i> expression in zebrafishSemantic proximity Read ↗

Surprising new roles for PU.1 in the adaptive immune response.Semantic proximity Read ↗

Differential involvement of PU.1 and Id2 downstream of TGF-β1 during Langerhans-cell commitmentSemantic proximity Read ↗

Alternative Activation of Macrophages Is Accompanied by Chromatin Remodeling Associated with Lineage-Dependent DNA Shape Features Flanking PU.1 Motifs.Semantic proximity Read ↗

Regulation of B lymphocyte and macrophage development by graded expression of PU.1.Semantic proximity Read ↗

The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter.Semantic proximity Read ↗

Functional analysis of PU.1 domains in monocyte-specific gene regulation.Semantic proximity Read ↗

Pumilio-dependent localization of mRNAs at the cell front coordinates multiple pathways required for chemotaxis.Semantic proximity Read ↗

PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.