Article

Zbtb14 regulates monocyte and macrophage development through inhibiting <i>pu.1</i> expression in zebrafish

2022-07-04

Abstract excerpt

Macrophages and their precursor cells, monocytes, are the first line of defense of the body against foreign pathogens and tissue damage. Although the origins of macrophages are diverse, some common transcription factors (such as PU.1) are required to ensure proper development of monocytes/macrophages. Here we report that the deficiency of zbtb14 , a transcription repressor gene belonging to ZBTB family, leads to...

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Literature Corpus work: 27adbcc3-fe4e-5fe4-9b4d-4f2e20c5ba1e
DOI: 10.1101/2022.07.03.498625

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