Article
Genetics of basal cell carcinoma.
The Australasian journal of dermatology - 1 May 2010
de Zwaan Sally E, Haass Nikolas K
Abstract excerpt
Basal cell carcinoma is the most common human malignancy in populations of European origin, and Australia has the highest incidence of basal cell carcinoma in the world. Great advances in the understanding of the genetics of this cancer have occurred in recent years. Mutations of the patched 1 gene (PTCH1) lead to basal cell carcinoma predisposition in Gorlin syndrome. PTCH1 is part of the hedgehog signalling...
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