[Frontotemporal dementia in association with a family history of dementia and ApoE polymorphism].

doi:10.1007/s00115-009-2822-1

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Article

[Frontotemporal dementia in association with a family history of dementia and ApoE polymorphism].

Der Nervenarzt - 1 Jan 2010

Zintl M, Petkov M, Schmitz G, Hajak G, Klünemann H-H

Abstract excerpt

OBJECTIVE: To examine the association between apolipoprotein E (ApoE) and a family history of dementia in 1st- and 2nd-degree relatives of patients with frontotemporal dementia (FTD) with a dementia onset by age 70. METHODS: The study included 494 dementia patients (73 FTD patients) and 82 cognitively normal spousal control subjects. Neuropsychiatric examination, Consortium To Establish a Registry on Alzheimer's...

Topics

Aged
Apolipoproteins E
Female
Frontotemporal Dementia
Genetic Predisposition to Disease
Genome-Wide Association Study
Germany
Humans
Incidence
Male
Polymorphism, Single Nucleotide
Risk Assessment
Risk Factors

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Open in PubMed

Identifiers

PMID: 19629426
DOI: 10.1007/s00115-009-2822-1

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