Article
Family history and APOE-4 genetic risk in Alzheimer's disease.
Neuropsychology review - 1 Sept 2012
Donix Markus, Small Gary W, Bookheimer Susan Y
Abstract excerpt
Identifying risk factors for Alzheimer's disease, such as carrying the APOE-4 allele, and understanding their contributions to disease pathophysiology or clinical presentation is critical for establishing and improving diagnostic and therapeutic strategies. A first-degree family history of Alzheimer's disease represents a composite risk factor, which reflects the influence of known and unknown susceptibility...
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