Article
Familial aggregation in frontotemporal dementia.
Neurology - 1 Jun 1998
Stevens M, van Duijn C M, Kamphorst W, de Knijff P, Heutink P, van Gool W A, Scheltens P, Ravid R, Oostra B A, Niermeijer M F, van Swieten J C
Abstract excerpt
OBJECTIVE AND BACKGROUND: Frontotemporal dementia (FTD) is a common, non-Alzheimer's dementia. Its familial occurrence has been reported, but the frequency of positive family history is unknown. METHODS: We carried out a nationwide genetic-epidemiologic study of FTD in the Dutch population of 15 million people. The family history of dementia was analyzed in 74 FTD patients and 561 age- and gender-matched control...
Topics
- Adult
- Age of Onset
- Aged
- Aged, 80 and over
- Apolipoproteins E
- Chromosomes, Human, Pair 17
- Dementia
- Female
- Frontal Lobe
- Genotype
- Humans
- Male