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Article

TGF-beta I gene polymorphism in heart transplant recipients--effect on renal function.

Annals of transplantation - 1 Jan 2001

Lácha J, Hubácek J A, Potmĕsil P, Viklický O, Málek I, Vítko S

Abstract excerpt

Renal dysfunction is a severe late complication of heart transplantation (HTx). Transforming growth factor beta I (TGF beta I) is a potent multifunctional cytokine with profibrogeneic effect. TGF beta I gene polymorphism correlates with cytokine production. In the present study, we looked for a predictor of renal insufficiency after HTx. In 175 HTx pts and 268 controls, polymorphism in the signal peptide of the...

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PMID: 11803605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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