Article
Association of C-509T and T869C polymorphisms of transforming growth factor-beta1 gene with chronic allograft nephropathy and graft survival in Korean renal transplant recipients.
Transplantation proceedings - 1 Sept 2008
Cho J-H, Huh S, Kwon T-G, Choi J-Y, Hur I-K, Lee E-Y, Park S-H, Kim Y-L, Kim C-D
Abstract excerpt
PURPOSE: Transforming growth factor-beta1 (TGF-beta1) has been associated with the promotion of renal allograft interstitial fibrosis and thereby chronic allograft nephropathy (CAN). The literature on TGF-beta1 polymorphisms and their importance in graft survival and CAN is not conclusive. METHODS: TGF-beta1 gene polymorphisms (C-509T and T869C) were examined in a group of 207 Korean renal transplant recipients...
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