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Article

Is low-frequency distribution of TGF-beta genotype associated with increased risk for end-stage renal disease?

DNA and cell biology - 1 Mar 2007

Mittal Rama Devi, Manchanda Parmeet Kaur

Abstract excerpt

End-stage renal disease has been associated with an inflammatory state. TGF-beta plays a critical role in antiinflammation counteracting inflammatory cytokines, wound healing, and tissue repair. We, therefore, speculated the protective role of TGF-beta in renal inflammation rather than inducing fibrosis. Three polymorphisms of TGF-beta (713-8delC), i.e., C deletion in intron sequence 8 base prior to exon-5 by...

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PMID: 17417945
DOI: 10.1089/dna.2006.0520

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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