Article
Incidence and distribution of experimental metastases in mutant mice with defective organ microenvironments (genotypes Sl/Sld and W/Wv).
Cancer research - 15 Apr 1992
Arguello F, Furlanetto R W, Baggs R B, Graves B T, Harwell S E, Cohen H J, Frantz C N
Abstract excerpt
Mice carrying mutations at the Sl (steel) and W (dominant white spotting) loci develop abnormalities on 3 migratory embryonic stem cell populations: hematopoietic stem cells, neural crest-derived melanocytes, and primordial germ cells. Transplantation experiments have indicated that the Sl locus...
Topics
- Animals
- Bone Neoplasms
- Female
- Heart Neoplasms
- Kidney Neoplasms
- Mice
- Mutation
- Neoplasm Metastasis
- Organ Specificity
- Ovarian Neoplasms
- Phenotype
- Stomach Neoplasms
