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Article

Role of PROP1 in pituitary gland growth.

Molecular endocrinology (Baltimore, Md.) - 1 Mar 2005

Ward Robert D, Raetzman Lori T, Suh Hoonkyo, Stone Brandon M, Nasonkin Igor O, Camper Sally A

Abstract excerpt

Mutations in the PROP1 transcription factor gene lead to reduced production of thyrotropin, GH, prolactin, and gonadotropins as well as to pituitary hypoplasia in adult humans and mice. Some PROP1-deficient patients initially exhibit pituitary hyperplasia that resolves to hypoplasia. To understand this feature and to explore the mechanism whereby PROP1 regulates anterior pituitary gland growth, we carried out...

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Source

Identifiers

PMID: 15591534
DOI: 10.1210/me.2004-0341

Genes

PROP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of PROP1 in pituitary gland growth.PMID 15591534Read ↗

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