Article
CD14 C(-159)T polymorphism is a risk factor for development of pulmonary tuberculosis.
The Journal of infectious diseases - 1 Dec 2007
Rosas-Taraco Adrian G, Revol Agnes, Salinas-Carmona Mario C, Rendon Adrian, Caballero-Olin Guillermo, Arce-Mendoza Alma Y
Abstract excerpt
BACKGROUND: Neither the expression of CD14 and Toll-like receptor 4 (TLR4) on monocytes' surface nor the mutations CD14 -159TT and TLR4 Asp299Gly have yet been evaluated as risk factors for development of pulmonary tuberculosis (TB) in the Mexican population. METHODS: Level of membrane CD14 (mCD14) and membrane TLR4 (mTLR4) were determined by flow cytometry, in 104 patients with pulmonary TB (before and after...
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