Article
Structure and function of carnitine acyltransferases.
Annals of the New York Academy of Sciences - 1 Nov 2004
Jogl Gerwald, Hsiao Yu-Shan, Tong Liang
Abstract excerpt
Carnitine acyltransferases catalyze the exchange of acyl groups between carnitine and coenzyme A (CoA). These enzymes include carnitine acetyltransferase (CrAT), carnitine octanoyltransferase (CrOT), and carnitine palmitoyltransferases (CPTs). CPT-I and CPT-II are crucial for the beta-oxidation of long-chain fatty acids in the mitochondria by enabling their transport across the mitochondrial membrane. The...
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