Article
Multi-subunit acetyl-CoA carboxylases.
Progress in lipid research - 1 Sept 2002
Cronan John E, Waldrop Grover L
Abstract excerpt
Acetyl-CoA carboxylase (ACC) catalyses the first committed step of fatty acid synthesis, the carboxylation of acetyl-CoA to malonyl-CoA. Two physically distinct types of enzymes are found in nature. Bacterial and most plant chloroplasts contain a multi-subunit ACC (MS-ACC) enzyme that is readily dissociated into its component proteins. Mammals, fungi, and plant cytosols contain the second type of ACC, a single...
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