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Article

Polymorphisms in factor II and factor VII genes modulate oral anticoagulation with warfarin.

Haematologica - 1 Dec 2004

D'Ambrosio Rosa Lucia, D'Andrea Giovanna, Cappucci Filomena, Chetta Massimiliano, Di Perna Pasquale, Brancaccio Vincenzo, Grandone Elvira, Margaglione Maurizio

Abstract excerpt

BACKGROUND AND OBJECTIVES: There is very considerable inter-individual variability in warfarin dosages necessary to achieve target therapeutic anticoagulation. The variability is largely genetically determined but can only partly be explained by genetic variability in the cytochrome CYP2C9 locus. Polymorphisms within the genes coding for vitamin K-dependent proteins have been suggested to predict sensitivity to...

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PMID: 15590403

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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