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Article

A haplotype of CYP2C9 associated with warfarin sensitivity in mechanical heart valve replacement patients.

British journal of clinical pharmacology - 1 Aug 2010

Lee Su-Jun, Jang Yin Jin, Cha Eun-Young, Kim Ho-Sook, Lee Sang Seop, Shin Jae-Gook

Abstract excerpt

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT * CYP2C9 single nucleotide polymorphisms (SNPs) are important in safe and effective oral anticoagulation with warfarin use. * Although CYP2C9*2 and *3 are important genetic factors for the warfarin dose, one of the CYP2C9 SNPs, IVS-65G>C, has been suggested to be associated with warfarin sensitivity. However, as of yet, there has been no explanation about the possible...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20653674
DOI: 10.1111/j.1365-2125.2010.03688.x
PMCID: PMC2911551

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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