Article
-238 and +489 TNF-alpha along with TNF-RII gene polymorphisms associate with the diffuse phenotype in patients with Systemic Sclerosis.
Immunology letters - 15 Jan 2005
Tolusso Barbara, Fabris Martina, Caporali Roberto, Cuomo Giovanna, Isola Miriam, Soldano Franca, Montecucco Carlomaurizio, Valentini Gabriele, Ferraccioli Gianfranco
Abstract excerpt
OBJECTIVE: To investigate possible associations of TNF-alpha and TNF-RII gene polymorphisms with diffuse or limited skin involvement phenotype in a cohort of Systemic Sclerosis (SSc) patients. METHODS: One-hundred and fourteen consecutive SSc patients attending the referral centres of three academic hospitals in Italy (University of Naples, Pavia and Udine), 56 with the diffuse (dcSSc) and 58 with limited (lcSSc)...
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