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Article

TNF-308A and HLA-DR3 alleles contribute independently to susceptibility to systemic lupus erythematosus.

Arthritis and rheumatism - 1 Jan 2000

Rood M J, van Krugten M V, Zanelli E, van der Linden M W, Keijsers V, Schreuder G M, Verduyn W, Westendorp R G, de Vries R R, Breedveld F C, Verweij C L, Huizinga T W

Abstract excerpt

OBJECTIVE: To evaluate the respective contributions of tumor necrosis factor (TNF) promoter polymorphisms and HLA-DR alleles to susceptibility to systemic lupus erythematosus (SLE). METHODS: TNF-238G/A and 308G/A promoter polymorphisms and HLA-DRB1 alleles were determined in 99 consecutive Caucasian SLE patients and 177 Caucasian controls. Standard and Mantel-Haenszel odds ratios were calculated to assess the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10643708
DOI: 10.1002/1529-0131(200001)43:1<129::AID-ANR16>3.0.CO;2-S

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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