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Article

TNF-alpha and TNF-beta gene polymorphisms in systemic sclerosis.

Human immunology - 1 Nov 1999

Pandey J P, Takeuchi F

Abstract excerpt

Tumor necrosis factor (TNF)-alpha and TNF-beta, mediators of inflammatory responses, have been implicated in the pathogenesis of autoimmune diseases. The aim of this investigation was to determine whether two promoter region polymorphisms of the TNF-alpha gene (TNF-alpha -308 and TNF-alpha -238) and a determinant in the first intron of the TNF-beta gene (TNF-beta +252) affect susceptibility to systemic sclerosis...

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Identifiers

PMID: 10600011
DOI: 10.1016/s0198-8859(99)00105-6

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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