Article
Association between polymorphisms in the TNF region and systemic lupus erythematosus in the Italian population.
Tissue antigens - 1 Jun 1996
D'Alfonso S, Colombo G, Della Bella S, Scorza R, Momigliano-Richiardi P
Abstract excerpt
The purpose of this work was to the hypothesis that MHC encoded susceptibility factors for SLE lie in the TNF region. An association study was performed by analyzing 123 northern Italian SLE patients and 199 matched controls for three TNF markers: two polymorphisms in the TNFA promoter and the TNFa microsatellite. Haplotypic combinations of TNF markers were also compared in patients and controls. No significant...
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