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Article

Phenotypic characteristics of mouse lung adenoma induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

Molecular carcinogenesis - 1 Feb 2005

Okubo Chigusa, Morishita Yukio, Minami Yuko, Ishiyama Tadashi, Kano Junko, Iijima Tatsuo, Noguchi Masayuki

Abstract excerpt

The expression profile of adenoma induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mice was compared with that of normal lung tissue by suppression subtractive hybridization (SSH). The mRNAs of surfactant-associated protein A (SP-A) and lysozyme showed characteristically higher transcription in the adenoma tissue than in normal lung. High expression of both SP-A and lysozyme in tumor cells...

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PMID: 15584020
DOI: 10.1002/mc.20070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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