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Article

Spontaneous and vaccine induced AFP-specific T cell phenotypes in subjects with AFP-positive hepatocellular cancer.

Cancer immunology, immunotherapy : CII - 1 Dec 2007

Butterfield Lisa H, Ribas Antoni, Potter Douglas M, Economou James S

Abstract excerpt

We are investigating the use of Alpha Fetoprotein (AFP) as a tumor rejection antigen for hepatocellular carcinoma (HCC). We recently completed vaccination of 10 AFP+/HLA-A2.1+ HCC subjects with AFP peptide-pulsed autologous dendritic cells (DC). There were increased frequencies of circulating AFP...

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Share to alpha-Fetoproteins
Share to Cancer Vaccines
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD4-Positive T-Lymphocytes

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Share to Leukocytes, Mononuclear

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Source

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Identifiers

PMID: 17522860
DOI: 10.1007/s00262-007-0337-9
PMCID: PMC11030770

Genes

AFP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17522860-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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