Article
The transforming growth factor-beta1 gene polymorphism (G915C) is not associated with systemic lupus erythematosus.
Lupus - 1 Jan 2003
Schotte H, Willeke P, Rust S, Assmann G, Domschke W, Gaubitz M, Schlüter B
Abstract excerpt
Lymphocyte production of transforming growth factor (TGF)-beta1 is decreased in systemic lupus erythematosus (SLE). The lack of this immunoregulatory cytokine may contribute to the characteristic T cell disregulation and aberrant B cell stimulation in SLE patients. The less common C allele of the...
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