Article
False positive non-synonymous polymorphisms of G-protein coupled receptor genes.
FEBS letters - 10 Apr 2002
Small Kersten M, Seman Carrie A, Castator Alex, Brown Kari M, Liggett Stephen B
Abstract excerpt
Polymorphisms of G-protein coupled receptor (GPCR) genes are associated with disease risk and modification, and the response to receptor-directed therapy. Genomic sequencing ( approximately 1700 automated runs) from as many as 120 chromosomes from 60 multiethnic individuals was performed to confirm non-synonymous coding polymorphisms reported in the dbSNP database from 25 randomly selected GPCR genes. These...
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