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Article

Effect of polymorphisms in the cytochrome P450 CYP2C9 gene on warfarin anticoagulation.

Archives of pathology & laboratory medicine - 1 Dec 2004

Adcock Dorothy M, Koftan Charles, Crisan Domnita, Kiechle Frederick L

Abstract excerpt

CONTEXT: Warfarin is a widely used anticoagulant with efficacy in treatment and prevention of thrombosis. Patient management, however, is difficult because of interindividual variation in response to standard doses due to significant differences in metabolic rates. Warfarin metabolism is under genetic control, involving primarily the CYP2C9 gene encoding the enzyme that catalyzes the conversion of warfarin to...

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Identifiers

PMID: 15578879
DOI: 10.5858/2004-128-1360-EOPITC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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