Article
Effects of cytochrome P450 2C9 polymorphisms on phenprocoumon anticoagulation status.
Clinical pharmacology and therapeutics - 1 Nov 2004
Schalekamp Tom, Oosterhof Mirjam, van Meegen Erik, van Der Meer Felix J M, Conemans Jean, Hermans Mirjam, Meijerman Irma, de Boer Anthonius
Abstract excerpt
OBJECTIVE: Our objective was to assess whether there is an association between the presence of allelic variants of the gene for cytochrome P450 (CYP) 2C9 and anticoagulation problems during the initial phase of phenprocoumon treatment. METHODS: A prospective follow-up study was performed at 2 anticoagulation clinics in The Netherlands. Included subjects started phenprocoumon during the study period, had their...
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