Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The relationship between CYP2C9 gene polymorphisms and upper gastrointestinal bleeding in patients who used warfarin.

Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina - 1 Feb 2013

Ucar Mahmut, Alagozlu Hakan, Sahin Safak, Ozdemir Ozturk

Abstract excerpt

AIM: Oral anticoagulants are the most common used substance for treatment and prophylaxis of warfarin venous and arterial thromboembolic disorders in the world. Therapeutic index of warfarin is narrow. CYP2C9 is a hepatic microsomal enzyme and has a primary role in metabolism of warfarin and genetic variations of CYP2C9 may cause a serious effect on the response to warfarin in patients. The aim of this study was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Administration, Oral
Share to Anticoagulants

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C9

Share to Drug Administration Schedule

Share to Drug Monitoring

Share to Gastrointestinal Hemorrhage

Share to Thromboembolism

Share to Warfarin

Source

Identifiers

PMID: 23348161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The relationship between CYP2C9 gene polymorphisms and upper gastrointestinal bleeding in patients who used warfarin.PMID 23348161Read ↗

Association of CYP2C9 gene polymorphism with bleeding as a complication of warfarin therapy.Semantic proximity Read ↗

Analysis of CYP2C9 polymorphisms (*2 and *3) in warfarin therapy patients in Pakistan. Association of CYP2C9 polymorphisms (*2 and*3) with warfarin dose, age, PT and INR.Semantic proximity Read ↗

The influence of polymorphisms of VKORC1 and CYP2C9 on major gastrointestinal bleeding risk in anticoagulated patients.Semantic proximity Read ↗

Effect of polymorphisms in the cytochrome P450 CYP2C9 gene on warfarin anticoagulation.Semantic proximity Read ↗

CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: a HuGEnet systematic review and meta-analysis.Semantic proximity Read ↗

Polymorphism in CYP2C9 as a non-critical factor of warfarin dosage adjustment in Korean patients.Semantic proximity Read ↗

The bleeding risk during warfarin therapy is associated with the number of variant alleles of CYP2C9 and VKORC1 genes.Semantic proximity Read ↗

Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy.Semantic proximity Read ↗

CYP2C19 polymorphism in Korean patients on warfarin therapy.Semantic proximity Read ↗

Influence of CYP2C9 and VKORC1 genotypes on the risk of hemorrhagic complications in warfarin-treated patients: a systematic review and meta-analysis.Semantic proximity Read ↗

Frequency of CYP2C9 genotypes among Omani patients receiving warfarin and its correlation with warfarin dose.Semantic proximity Read ↗

Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.