Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The kgmB gene, encoding ribosomal RNA methylase from Streptomyces tenebrarius, is autogenously regulated.

Archives of microbiology - 1 Dec 2004

Vajic Sandra, Anastasov Natasa, Vasiljevic Branka

Abstract excerpt

The KgmB methylase (the kanamycin-gentamicin resistance methylase from Streptomyces tenebrarius) acts at G-1405 of 16S rRNA within the sequence CGUCA that is also found 6 bp in front of ribosomal binding site of the kgmB gene. The kgmBColon, two colonslacZ gene and operon fusions were used in order to test for translational autoregulation of kgmB gene. Overexpression of kgmB either in cis or in trans drastically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Artificial Gene Fusion
Share to beta-Galactosidase
Share to Gene Expression Regulation, Enzymologic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Kanamycin Resistance

Share to Lac Operon

Share to Methyltransferases

Share to RNA, Bacterial

Share to Streptomyces

Source

Identifiers

PMID: 15578257
DOI: 10.1007/s00203-004-0731-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The kgmB gene, encoding ribosomal RNA methylase from Streptomyces tenebrarius, is autogenously regulated.PMID 15578257Read ↗

Novel Plasmid-Mediated 16S rRNA Methylase, RmtC, Found in a Proteus mirabilis Isolate Demonstrating Extraordinary High-Level Resistance against Various AminoglycosidesSemantic proximity Read ↗

Amplification of the entire kanamycin biosynthetic gene cluster during empirical strain improvement of Streptomyces kanamyceticus.Semantic proximity Read ↗

Critical residues for cofactor binding and catalytic activity in the aminoglycoside resistance methyltransferase Sgm.Semantic proximity Read ↗

Inactivation of KsgA, a 16S rRNA methyltransferase, causes vigorous emergence of mutants with high-level kasugamycin resistance.Semantic proximity Read ↗

Novel Plasmid-Mediated 16S rRNA m <sup>1</sup> A1408 Methyltransferase, NpmA, Found in a Clinically Isolated <i>Escherichia coli</i> Strain Resistant to Structurally Diverse AminoglycosidesSemantic proximity Read ↗

Mutations in rsmG, encoding a 16S rRNA methyltransferase, result in low-level streptomycin resistance and antibiotic overproduction in Streptomyces coelicolor A3(2).Semantic proximity Read ↗

Identification of the RsmG methyltransferase target as 16S rRNA nucleotide G527 and characterization of Bacillus subtilis rsmG mutants.Semantic proximity Read ↗

The Novel Transcriptional Regulator LmbU Promotes Lincomycin Biosynthesis through Regulating Expression of Its Target Genes in Streptomyces lincolnensisSemantic proximity Read ↗

The S(MK) box is a new SAM-binding RNA for translational regulation of SAM synthetase.Semantic proximity Read ↗

Cloning and characterization of two genes from Streptomyces lividans that confer inducible resistance to lincomycin and macrolide antibiotics.Semantic proximity Read ↗

Novel GC-rich DNA-binding compound produced by a genetically engineered mutant of the mithramycin producer Streptomyces argillaceus exhibits improved transcriptional repressor activity: implications for cancer therapy.Semantic proximity Read ↗

Effects of dual deletion of glnR and mtrA on expression of nitrogen metabolism genes in Streptomyces venezuelaeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.