Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of the RsmG methyltransferase target as 16S rRNA nucleotide G527 and characterization of Bacillus subtilis rsmG mutants.

Journal of bacteriology - 1 Aug 2007

Nishimura Kenji, Johansen Shanna K, Inaoka Takashi, Hosaka Takeshi, Tokuyama Shinji, Tahara Yasutaka, Okamoto Susumu, Kawamura Fujio, Douthwaite Stephen, Ochi Kozo

Abstract excerpt

The methyltransferase RsmG methylates the N7 position of nucleotide G535 in 16S rRNA of Bacillus subtilis (corresponding to G527 in Escherichia coli). Disruption of rsmG resulted in low-level resistance to streptomycin. A growth competition assay revealed that there are no differences in fitness between the rsmG mutant and parent strains under the various culture conditions examined. B. subtilis rsmG mutants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacillus subtilis
Share to Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Escherichia coli Proteins

Share to Methyltransferases

Share to Mutation

Share to RNA, Ribosomal

Share to RNA, Ribosomal, 16S

Share to Streptomycin

Source

Open in PubMed Open full text

Identifiers

PMID: 17573471
DOI: 10.1128/JB.00558-07
PMCID: PMC1952054

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of the RsmG methyltransferase target as 16S rRNA nucleotide G527 and characterization of Bacillus subtilis rsmG mutants.PMID 17573471Read ↗

Mutations in rsmG, encoding a 16S rRNA methyltransferase, result in low-level streptomycin resistance and antibiotic overproduction in Streptomyces coelicolor A3(2).Semantic proximity Read ↗

Loss of U1498 methylation in 16S rRNA by RsmE methyltransferase associates its role with aminoglycoside resistance in mycobacteriaSemantic proximity Read ↗

Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG.Semantic proximity Read ↗

Inactivation of KsgA, a 16S rRNA methyltransferase, causes vigorous emergence of mutants with high-level kasugamycin resistance.Semantic proximity Read ↗

Deletion of RsmE 16S rRNA methyltransferase leads to low level increase in aminoglycoside resistance in <i>Mycobacterium smegmatis</i>Semantic proximity Read ↗

Antibiotic resistance evolved via inactivation of a ribosomal RNA methylating enzyme.Semantic proximity Read ↗

The mthA mutation conferring low-level resistance to streptomycin enhances antibiotic production in Bacillus subtilis by increasing the S-adenosylmethionine pool size.Semantic proximity Read ↗

Activation of secondary metabolite-biosynthetic gene clusters by generating rsmG mutations in Streptomyces griseus.Semantic proximity Read ↗

Ribosomal A site binding pattern differs between Arm methyltransferases from clinical pathogens and a natural producer of aminoglycosides.Semantic proximity Read ↗

Mutations in 16S rRNA in Escherichia coli at methyl-modified sites: G966, C967, and G1207.Semantic proximity Read ↗

Mechanisms of streptomycin resistance: selection of mutations in the 16S rRNA gene conferring resistance.Semantic proximity Read ↗

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.