Article
Long-term persistence of primary genotypic resistance after HIV-1 seroconversion.
Journal of acquired immune deficiency syndromes (1999) - 15 Dec 2004
Pao David, Andrady Ushan, Clarke Janette, Dean Gillian, Drake Susan, Fisher Martin, Green Tanya, Kumar Siva, Murphy Maurice, Tang Alan, Taylor Stephen, White David, Underhill Gillian, Pillay Deenan, Cane Patricia
Abstract excerpt
Primary infection with drug-resistant HIV-1 is well documented. We have followed up patients infected with such viruses to determine the stability of resistance-associated mutations. Fourteen patients who experienced primary infection with genotypic evidence of resistance were followed for up to 3 years. Drug resistance-associated mutations persisted over time in most patients studied. In particular, M41L, T69N,...
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